“I don’t think there is an ideal time [to play Manchester United],” said Brentford boss Thomas Frank.
“In general I don’t believe in if it’s a perfect situation to play them in or a bad situation to play them in.
“But one thing is for sure, they’ve got a new manager, a brilliant manager, I think he’s done a fantastic job in his earlier jobs, so they’re very interested in doing everything they can to make it a success with the players.”
The Bees’ manager added: “They lost the first game, so if you lost a game the most common response (is) to really want to improve and do well. So it’s going to be extremely difficult tomorrow.
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“I think there is no doubt that Manchester United are favourites, they can’t afford not to win against us tomorrow.
“Of course, we believe and we will do everything we can to beat them and I believe we have a good chance.”
The Red Devils lost the opening Premier League day clash with Brighton and are in dire need of a win on Saturday.
Anthony Martial and Victor Lindelof are ruled out for the game but the rest of the squad is fit and ready.